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Message from the Institute Director

The Research Institute for Biomedical Sciences is a comprehensive research organization engaged in multifaceted studies in the field of life sciences, which has undergone rapid advancement in recent years. The institute has seven core research division groups, divisions for collaborative research projects involving researchers from within and outside the university, and various support facilities, including those specializing in computer networks. The institute is engaged in advanced research in an environment that encourages close cooperation.

The life sciences seek to understand the nature of biomedical phenomena associated with people and all other life forms at the molecular and genetic levels. Such an understanding can contribute to the welfare of mankind by revealing pathogenic mechanisms of life-threatening intractable diseases. The life sciences also provide a framework for investigating the origins of life and retracing the history of evolution, which could give us a glimpse of the future of mankind. In these ways, the life sciences represent an extremely important academic discipline that is attracting high hopes from the public.

Hiroyasu Esumi, Director, Research Institute for Biomedical Sciences

Research Institute Division Groups

Division of Immunobiology

This division covers cutting-edge research fields that seek to better understand the mechanism of the immune system, which protects the body from pathogenic microorganisms, at the cellular, molecular and genetic levels. The division's research is focused on intractable diseases such as cancer and autoimmunity, as well as important biomedical phenomena such as ageing and allergies.

Division of Molecular Biology

This research division seeks to understand biomedical phenomena in terms of structure and function of genes and DNA using molecular biology techniques such as gene recombination. Supported by state-of-the-art research facilities and equipment, the division is pursuing research into the mechanisms of immunity, organ formation, apoptosis and carcinogenesis, among other fields.

Division of Biosignaling

This division focuses on understanding the molecular mechanism of dynamic and complex biological systems such as brain and immune system by using advanced imaging techniques, biophysical tools, and system-biological approach. The elucidation of molecular mechanism underlying axon outgrowth/guidance, membrane trafficking implicated in neural homeostasis, and peptide recognition by T cell receptors will provide clues to develop clinical applications for a variety of diseases.

Division of Molecular Pathology

This research division seeks to understand a picture of the homeostatic regulation by cytokines. Aberrations of the cytokine system is known to tightly associate with various immunological disorders. Our ultimate goal is to understand cytokine biology to control immune responses. This can be a powerful way to control disease. Therefore, this division pursues research investigating the mechanisms underlying the cytokine related pathogenic situations, including infectious diseases, autoimmune diseases, and allergy.

Division of Development and Aging

The research conducted in this division focuses the organogenesis of tissues and their homeostatic maintenance throughout the life time, from the view point of interaction of the tissue stem cell with its specific microenvironment. Understanding of the molecular mechanisms regulating these processes involved in cellular differentiation, growth, aging and death, provides a basic information helping to establish novel methods manipulating these biological processes for the application to the regenerative medicine.

Division of Experimental Animal Immunology

This new division was established in the 2008 academic year to promote teaching and research in the field of laboratory animal science. The division studies animals with modified genes, specifically genes involved in the differentiation and functioning of immune cells and hemopoietic cells, in order to clarify the roles of those molecules in diseases.

Division of Clinical Research

The main focus of this division is development of revolutional medicine and medical equipment by promoting collaborations between basic biomedical and engineering researches and actual clinical researchers. Development of preventive medicine and/or food for cancer and sarcopenia is also within the scope of this division.

Division of Intramural Cooperation

The Division of Intramural Cooperation conducts joint research projects outside the scope of each of the five core research division groups. Within the division, research teams spanning various faculties and departments jointly study new proposals concerning life science.

Division of Extramural Cooperation

The Division of Extramural Cooperation is a joint research division including participation from private- and public-sector research institutes. The division absorbs basic research techniques while developing original research themes and conducting R&D activities from a broad perspective.

Research Institute for Biomedical Sciences
Director Hiroyasu Esumi
Division of Immunobiology Professor Ryo Abe
Junior Associate Professor Yuki Obata
Division of Molecular Biology Professor Daisuke Kitamura
Associate Professor Ryushin Mizuta
Associate Professor Etsuko Miyamoto-Sato
Assistant Professor Kei Haniuda
Assistant Professor Masaaki Ozawa
Division of Biosignaling Professor Takeshi Nakamura
Associate Professor Haruo Kozono
Assistant Professor Tomohisa Nanao
Division of Molecular Pathology Professor Masato Kubo
Associate Professor Naoko Nakano
Assistant Professor Shinya Tanaka
Division of Development and Aging Professor Ryo Goitsuka
Assistant Professor Akihisa Oda
Division of Experimental Animal Immunology Professor Yoichiro Iwakura
Junior Associate Professor Shuhei Ogawa
Assistant Professor Saku Tou
Assistant Professor Tomoyuki Shimazu
Assistant Professor Masanori Murayama
Technical Assistant Sachiko Kubo
Division of Clinical Research Professor Hiroyasu Esumi
Shared equipment Technical Assistant Yasushi Hara